5. wounded—a bodily wound; not mere mental sorrow; literally, "pierced"; minutely appropriate to Messiah, whose hands, feet, and side were pierced (Ps 22:16). The Margin, wrongly, from a Hebrew root, translates, "tormented."
for … for—(Ro 4:25; 2Co 5:21; Heb 9:28; 1Pe 2:24; 3:18)—the cause for which He suffered not His own, but our sins.
bruised—crushing inward and outward suffering (see on Isa 53:10).
chastisement—literally, the correction inflicted by a parent on children for their good (Heb 12:5-8, 10, 11). Not punishment strictly; for this can have place only where there is guilt, which He had not; but He took on Himself the chastisement whereby the peace (reconciliation with our Father; Ro 5:1; Eph 2:14, 15, 17) of the children of God was to be effected (Heb 2:14).
upon him—as a burden; parallel to "hath borne" and "carried."
stripes—minutely prophetical of His being scourged (Mt 27:26; 1Pe 2:24).
healed—spiritually (Ps 41:4; Jer 8:22).