22. This second brother, Birks supposes to be Trophimus: for a Macedonian is not meant (2Co 9:4) probably the same as was sent before with Titus (2Co 12:18); and therefore sent from Ephesus, and probably an Ephesian: all this is true of Trophimus.
oftentimes … in many things—Join and translate as in the Greek, "many times in many things."
upon the great confidence which I have in you—"through the great confidence WHICH HE HAS towards you" [Alford]. Bengel better supports English Version, "We have sent … through the confidence WHICH WE FEEL in regard to your liberality."