22. Which—things, namely, the three things handled, touched, and tasted.
are to perish—literally, "are constituted (by their very nature) for perishing (or 'destruction by corruption') in (or 'with') their using up (consumption)." Therefore they cannot really and lastingly defile a man (Mt 15:17; 1Co 6:13).
after—according to. Referring to Col 2:20, 21. All these "ordinances" are according to human, not divine, injunction.
doctrines—Greek, teachings." Alford translates, "(doctrinal) systems."