16. book of the Lord—the volume in which the various prophecies and other parts of Scripture began henceforward to be collected together (Isa 30:8; Da 9:2).
Seek—(so Isa 8:16, 20; Joh 5:39; 7:52).
no one … fail—of these prophecies (Mt 5:18).
none shall want … mate—image from pairing of animals mentioned, Isa 34:15 ("mate"); no prediction shall want a fulfilment as its companion. Or rather, "none of these wild animals (just spoken of) shall be wanting: none shall be without its mate" to pair and breed with, in desolate Idumea.
my … his—Such changes of person are frequent in Hebrew poetry.
them—the wild beasts.